Ketamine abuse damages bladder, kidneys

NEW YORK (Reuters Health) - Ketamine, widely abused as a party drug and sometimes known as Special K, can cause inflammation and contraction of the bladder leading to possibly irreversible kidney damage, according to a report from Hong Kong.

Ketamine is mostly used as a veterinary anesthetic. In humans, it causes hallucinations and high blood pressure. It became widely abused in some parts of the world by the 1990s, and has since been banned or classified as a controlled substance in several countries.

“Street-ketamine abuse is not only a drug problem but might be associated with a serious urological condition causing a significant burden to healthcare resources,” Dr. Peggy Sau-Kwan Chu and colleagues write in the medical journal BJU International.

In their study, Chu, from Tuen Mun Hospital, Hong Kong, China, and others describe problems that developed in 59 ketamine abusers who were seen at Hong Kong hospitals from March 2000 to December 2007.

All of the subjects had moderate to severe lower urinary tract symptoms, such as urgency, frequency, and difficulty urinating.

Visual examination with a cystoscope revealed an inflamed bladder in 42 of these individuals, and biopsies showed that 12 of them had a more serious condition called interstitial cystitis.

On further testing, 47 patients were found to have overactive bladder or decreased bladder elasticity, the team reports.

Damage to one or both kidneys was seen on ultrasound in 30 patients, and four of them had areas of dead kidney tissue.

“Abstinence from ketamine abuse is strongly advocated before any irreversible damage to the urinary tract occurs,” Chu and her colleagues emphasize.

People who’ve used ketamine recreationally should seek early urological assessment, they advise. This may “help to reduce not only the detrimental effects to the abusers, but also the health costs to society.”

SOURCE: BJU International, December 2008.

Source

--------------------------------------------------------------------------------------------
Related Posts:


NEW YORK (Reuters Health) - The odds are high that a woman who is prescribed an “anticholinergic” drug to relieve urinary incontinence or other lower urinary tract symptom will discontinue the medication not long after starting it, a study suggests. This is true regardless of the class of medication used. Two examples of anticholinergic drugs that

Full Post: Drug adherence poor in women with urinary trouble
--------------------------------------------------------------------------------------------

By Susan Heavey WASHINGTON (Reuters) - Alpharma Inc’s powerful painkiller Embeda, which contains morphine sulfate and Duramorph, may not thwart drug abusers despite design features aimed at discouraging its misuse, U.S. regulatory staff said in documents released on Wednesday. The drugmaker tested the effects of the design features only when the pill was misused orally, but addicts

Full Post: FDA staff cite abuse concern with Embeda
--------------------------------------------------------------------------------------------

By Tan Ee Lyn HONG KONG (Reuters) - Hong Kong will soon begin testing meat, vegetables and processed food for melamine, a move that underlines concerns about environmental contamination and food safety, experts say. Thousands of children in China fell sick with kidney problems in recent months after consuming milk that had been mixed with the plastic-making

Full Post: Hong Kong to test meat, vegetables for melamine
--------------------------------------------------------------------------------------------

HONG KONG (Reuters) - Scientists in China and Hong Kong have established for the first time in a study that consuming the plastic-making chemical melamine can cause kidney stones in people. At least six children died and 290,000 fell ill in China last year after consuming milk formula tainted with melamine, which was added to cheat

Full Post: Experts draw link between tainted milk, kidney stones
--------------------------------------------------------------------------------------------

NEW YORK (Reuters Health) - Women who are the victims of domestic abuse tend to take their infants to the doctor more often than other mothers do, a new study finds. Knowing this, researchers say, could help doctors spot women who are at heightened risk of abuse from their partners. The findings, published in the Journal of

Full Post: Abused moms seek more medical care for infants

Site Navigation

Most Read

Search

Most Read

Contact

  • kinwrite.com@gmail.com