UK’s first breast cancer gene screen baby born

LONDON (Reuters) - The first baby girl in Britain to have been screened before conception for a genetic form of breast cancer has been born, doctors said on Friday.

While a first in Britain, the strategy has been used elsewhere across the world to screen for the cancer-related BRCA1 gene variant, and the technique has also been previously applied by British doctors to avoid the transmission of other cancers and diseases.

In the current case, doctors at University College Hospital in London (UCL) had created a number of embryos through in vitro fertilization (IVF) for the baby’s parents and screened them for the variant BRCA1 gene.

Women who carry this genetic variation have an 80 percent chance of developing breast cancer and a 60 percent chance of suffering ovarian cancer during their lifetime, and the couple’s children were at very high risk of inheriting the gene. However, carrying the gene does not make cancer inevitable.

“This little girl will not face the specter of developing this genetic form of breast cancer or ovarian cancer in her adult life,” said Paul Serhal, Medical Director of the Assisted Conception Unit at UCL.

“The parents will have been spared the risk of inflicting this disease on their daughter. The lasting legacy is the eradication of the transmission of this form of cancer that has blighted these families for generations.”

The mother and baby girl, who have not been identified, are doing very well.

The embryo was chosen using preimplantation genetic diagnosis (PGD), which involves testing cells to see if they contain the faulty gene. An embryo found not have the gene was then implanted into the mother.

The Human Fertilization and Embryology Authority (HFEA), the regulator which had to approve the procedure, said the chosen embryo had not been genetically manipulated or programed.

Source

--------------------------------------------------------------------------------------------
Related Posts:


By Megan Rauscher NEW YORK (Reuters Health) - Among United States Latinas, a greater degree of European genetic ancestry is associated with an increased risk of breast cancer, the results of a new study indicate. This could be due to environmental factors, genetic factors, or the interplay of the two, the study team suggests. Latina women generally

Full Post: European origin may up Latinas’ breast cancer risk
--------------------------------------------------------------------------------------------

CHICAGO (Reuters) - Genes that increase the risk of heart disease in the general population carry an even greater risk of heart trouble in diabetics, U.S. researchers said on Tuesday. The findings may help better identify which diabetics are at risk for heart disease and could lead to new treatments, they said. “Coronary artery disease is one

Full Post: Genes that raise heart risks amplified in diabetics
--------------------------------------------------------------------------------------------

By Will Dunham WASHINGTON (Reuters) - Women with a family history of breast cancer but who test negative for two genetic mutations commonly linked to it still have a very high risk of developing the disease, Canadian researchers said on Monday. These women are four times more likely to develop breast cancer than the average woman, translating

Full Post: Family history key in figuring breast cancer risk
--------------------------------------------------------------------------------------------

By Julie Steenhuysen CHICAGO (Reuters) - A single gene appears to play a crucial role in deadly breast cancers, increasing the chances the cancer will spread and making it resistant to chemotherapy, U.S. researchers said on Monday. They found people with aggressive breast cancers have abnormal genetic alterations in a gene called MTDH, and drugs that block

Full Post: Scientists find a gene that makes cancer spread
--------------------------------------------------------------------------------------------

By Amy Norton NEW YORK (Reuters Health) - Obese women may have a higher risk of developing ovarian cancer than their thinner counterparts, a large study of U.S. women suggests. Ovarian cancer is a particularly deadly type of cancer because in the initial stages it typically has vague symptoms or none at all, making it difficult to

Full Post: Obesity may raise risk of ovarian cancer

Site Navigation

Most Read

Search