Quinolone antibiotics and Cimetidine
Abstract/Summary
Cimetidine reduces the clearance of pefloxacin from the body, ranitidine reduces the absorption of enoxacin but neither cimetidine nor ranitidine appear to interact with cipro.
Clinical evidence, mechanism, importance and management
Neither cimetidine nor ranitidine affect the pharmacokrnetics of cipro12-5 but a study of the concurrent use of cimetidine and pefloxacin showed that the AUC was increased [...]
Posted in Antibiotics