Scientists find 4 genes that drive metabolism

LONDON (Reuters) - Four genetic variations appear to determine the speed at which people burn up food, researchers said on Thursday, a finding that could one day see doctors offer their patients more individual care.

Differences in metabolism can make some people more susceptible to diseases such as diabetes and explain why response to diet, exercise and drugs to treat certain conditions varies from person to person.

Knowing right away how a person’s body will break down molecules in the blood that build up muscle and cells and provide energy could lead to better care, said Karsten Suhre, a researcher at the Helmholtz Center in Munich.

The researchers scanned the genes of 284 people and found four — FADS1, LIPC, SCAD and MCAD — linked to determining metabolic rates.

“These genes appear to be involved or play a key role in metabolism,” Suhre said in a telephone interview.

This potentially paves the way for more personalized health care in which doctors could use knowledge of a patient’s metabolism gleaned from their genetic make-up to determine treatment, he said.

This could prove particularly useful for treating conditions strongly linked to metabolism such as coronary artery disease and obesity, he added.

“These findings could result in a step toward personalized healthcare and nutrition based on a combination of genoytyping and metabolic characterization,” Suhre and colleagues wrote in the Public Library of Science Journal PLoS Genetics.

The study is available at: here

(Reporting by Michael Kahn; Editing by Sophie Hares)

Source

--------------------------------------------------------------------------------------------
Related Posts:


By Will Dunham WASHINGTON (Reuters) - A gene that affects how the kidneys process salt may help determine a person’s risk of high blood pressure, a discovery that could lead to better ways to treat the condition, researchers said on Monday. People with a common variant of the gene STK39 tend to have higher blood pressure levels

Full Post: Key gene linked to high blood pressure identified
--------------------------------------------------------------------------------------------

WASHINGTON (Reuters) - Researchers have identified six new gene mutations linked to obesity and said on Sunday they point to ways the brain and nervous system control eating and metabolism. “Today’s findings are a major step forward in understanding how the human body regulates weight,” Dr. Alan Guttmacher, Acting director of the National Human Genome Research

Full Post: Study finds six new gene mutations linked to obesity
--------------------------------------------------------------------------------------------

By Will Dunham WASHINGTON (Reuters) - Distinctive genetic changes occur in the cancer cells that trigger relapse in patients with the most common type of childhood cancer, according to a study that may offer new hope for beating the disease. Writing in the journal Science on Thursday, the scientists described key genetic differences in cancer cells of

Full Post: Scientists track genetic changes in leukemia
--------------------------------------------------------------------------------------------

NEW YORK (Reuters Health) - Having the so-called metabolic syndrome may raise the risk of chronic kidney disease in people with type 2 diabetes, researchers from China report. Metabolic syndrome refers to a cluster of risk factors for diabetes and heart disease — including abdominal obesity, high blood pressure, high blood sugar, low levels of “good”

Full Post: Metabolic syndrome predicts kidney disease
--------------------------------------------------------------------------------------------

By Michael Kahn LONDON (Reuters) - Many genes linked to various cancers do not appear to raise the risk of getting cancer after all, according to an analysis of hundreds of studies published on Tuesday. The findings highlight the need to exercise caution over the increasing number of studies associating common genetic variations with a range of

Full Post: Many studies needed to tie genes to cancer: study

Site Navigation

Most Read

Search