Vitamin E won’t prevent rheumatoid arthritis: study

NEW YORK (Reuters Health) - Taking vitamin E supplements does not reduce a woman’s risk of rheumatoid arthritis (RA), an analysis of data from the Women’s Health Study indicates.

“Despite plausible biologic mechanisms,” the present randomized, controlled trial does not show that long-term use of vitamin E supplements significantly decreases the risk of developing RA, Dr. Elizabeth W. Karlson and co-researchers conclude.

About 20 million people worldwide have RA — an autoimmune disease caused when the body confuses healthy tissues for foreign substances and attacks itself. The disease causes pain, stiffness and swelling in multiple joints, and inflammation can develop in other organs as well. Studies have suggested that RA raises heart risks.

Data from some previous “observational” studies have shown that diets high in antioxidants are associated with lower RA risk, Karlson and colleagues note in the journal Arthritis Care and Research.

As part of the Women’s Health Study, 39,144 women at least 45 years of old were randomly allocated to take vitamin E at a dose of 600 international units every other day or placebo.

During follow-up lasting 10 years on average, 50 women in the vitamin E group and 56 in the placebo group developed RA, Karlson and colleagues from Brigham and Women’s Hospital in Boston report.

This suggests that vitamin E supplementation does not significantly affect the risk of RA, they conclude.

SOURCE: Arthritis Care and Research, November 15, 2008.


Related Posts:

NEW YORK (Reuters Health) - In the large Women’s Antioxidant Cardiovascular Study, participants who took beta carotene, vitamin C, vitamin E, or a combination of supplements had no significant reductions in their risk of cancer. The clinical trial, which involved 7,627 women who were followed for an average of 9.4 years, was conducted by Dr. Jennifer

Full Post: No cancer risk reductions seen with antioxidants

By Will Dunham WASHINGTON (Reuters) - Beta carotene, vitamin C and vitamin E supplements taken for years failed to lower overall cancer risk in the latest study to cast doubt on the possibility that such dietary supplements can prevent cancer. The findings, published on Tuesday in the Journal of the National Cancer Institute, followed two other important

Full Post: Antioxidants fail again in cancer prevention study

NEW YORK (Reuters Health) - Lower blood levels of 25-hydroxyvitamin D, a protein that provides an acquire measure of vitamin D in the blood, are independently associated with an increased risk of developing high blood pressure, according to findings published in Hypertension. Studies have shown 25(OH)D levels and skin exposure to UVB radiation…are associated with lower

Full Post: Low vitamin D linked with high blood pressure

WASHINGTON (Reuters) - Neither vitamin C nor vitamin E supplements cuts the risk of cardiovascular disease including heart attack and stroke in a U.S. study published on Sunday. And a second study failed to show that taking low-dose aspirin helped prevent heart and artery disease among Japanese people with diabetes. Many people take vitamin supplements to try

Full Post: Vitamins C, E do not cut heart attack, stroke risk: study

NEW YORK (Reuters Health) - Older African-American, Native American and non-white Hispanic women are more likely to develop arthritis than their white counterparts, and the larger prevalence of obesity among these ethnic groups may help explain why, new research shows. Among 146,494 women participating in the Women’s Health Initiative — an ongoing study of an ethnically

Full Post: Ethnic differences in arthritis due to obesity

Site Navigation

Most Read