Thyroid disease often seen with celiac disease

NEW YORK (Reuters Health) - Individuals with celiac disease — a common digestive problem in which the body cannot breakdown and absorb a protein found in wheat — are at significantly increased risk for developing thyroid disorders, including hypothyroidism, hyperthyroidism and thyroiditis, investigators in Sweden have found.

The thyroid is a butterfly-shaped gland in the neck that produces hormones that regulate the body’s metabolism. In hypothyroidism, the gland is underactive, causing symptoms such as fatigue, sensitivity to cold, dry skin and weight gain.

In hyperthyroidism, the gland is overactive, causing symptoms such as excessive sweating, heat intolerance, and nervousness. However, in mild cases of hypo- or hyperthyroidism no symptoms are present. Thyroiditis describes inflammation of the thyroid gland.

Using data from Swedish national registers, researchers led by Dr. Peter Elfstrom at Orebro University Hospital, studied the long-term risk of thyroid disease in more than 14,000 individuals diagnosed with celiac disease between 1964 and 2003 and some 68,000 age- and gender-matched control subjects without celiac disease.

They found that people with celiac disease had a greater than fourfold increased risk of being diagnosed with hypothyroidism, a threefold increased risk of suffering hyperthyroidism, and a 3.6-fold increased risk of developing thyroiditis.

The reverse was also true, with the same level of statistical significance, for an increased risk of celiac disease in people with established hypothyroidism, hyperthyroidism and thyroiditis.

“The association was seen in all strata (males, females, children, and adults),” the team notes in the Journal of Clinical Endocrinology and Metabolism, “and did not vanish after adjustment for potential confounders including the presence of diabetes mellitus.”

“The positive association between celiac disease and thyroid disease may be due to shared genetic or immunological traits,” the researchers say.

SOURCE: Journal of Clinical Endocrinology and Metabolism, October 2008.


Related Posts:

WASHINGTON (Reuters) - Obese children may be damaging their thyroids, creating a vicious cycle of metabolism and overweight, Italian researchers reported on Wednesday. Obesity may cause inflammation that damages the thyroid, which secretes hormones to regulate metabolism and other important functions, Dr. Giorgio Radetti of the Regional Hospital of Bolzano in Italy and colleagues said. They evaluated

Full Post: Obese children risk thyroid damage

WASHINGTON (Reuters) - Here’s another thing that smoking while pregnant can do — it can damage both the mother’s and the baby’s thyroid function, British researchers reported on Tuesday. Cigarette smoke has been shown to cause babies to be born smaller, to make newborns more likely to die of sudden infant death syndrome, and even to

Full Post: Smoking when pregnant affects thyroid for both: study

NEW YORK (Reuters Health) - Children born “small for gestational age” — that is, significantly smaller than most babies born after the same number of weeks of pregnancy — appear to be at increased risk for rapid gains in weight and body fat during adulthood, researchers from Paris, France report. People born small for gestational age

Full Post: Effects of being born small extend to adulthood

Synthroid treats hypothyroidism and also goitre developed by cancer, hormone imbalances, radiation treatment or surgery. Synthroid should be taken in the morning about half an hour before eating anything. Take the drug with full glass of water. When you are on Synthroid medication, never deviate from your prescription. Always follow the direction of your doctor. Never

Full Post: Synthroid treats hypothyroidism

NEW YORK (Reuters Health) - Following gestational diabetes, a type of diabetes that developments during pregnancy and usually goes away after pregnancy, treatment with metformin or intensive lifestyle interventions can prevent or delay diabetes from becoming permanent in the postpartum period, new research shows. Lead author Dr. Robert E. Ratner at Medstar Research Institute in Hyattsville,

Full Post: Metformin can prevent postpartum diabetes

Site Navigation

Most Read